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Computational characterization of the binding mode between oncoprotein Ets‐1 and DNA‐repair enzymes

The Ets‐1 oncoprotein is a transcription factor that promotes target gene expression in specific biological processes. Typically, Ets‐1 activity is low in healthy cells, but elevated levels of expression have been found in cancerous cells, specifically related to tumor progression. Like the vast maj...

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Detalhes bibliográficos
Publicado no:Proteins
Main Authors: de Ruyck, Jerome, Brysbaert, Guillaume, Villeret, Vincent, Aumercier, Marc, Lensink, Marc F.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282593/
https://ncbi.nlm.nih.gov/pubmed/30019773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25578
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