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Computational characterization of the binding mode between oncoprotein Ets‐1 and DNA‐repair enzymes

The Ets‐1 oncoprotein is a transcription factor that promotes target gene expression in specific biological processes. Typically, Ets‐1 activity is low in healthy cells, but elevated levels of expression have been found in cancerous cells, specifically related to tumor progression. Like the vast maj...

詳細記述

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書誌詳細
出版年:Proteins
主要な著者: de Ruyck, Jerome, Brysbaert, Guillaume, Villeret, Vincent, Aumercier, Marc, Lensink, Marc F.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley & Sons, Inc. 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282593/
https://ncbi.nlm.nih.gov/pubmed/30019773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.25578
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