High-yield production of human Dicer by transfection of human HEK293-EBNA1 cells grown in suspension

BACKGROUND: Dicer is a 219-kDa protein that plays key roles in gene regulation, particularly as the ribonuclease III enzyme responsible for cleaving precursor miRNA substrates. Its enzymatic activity is highly regulated by protein factors, and this regulation can impact on the levels of miRNAs and m...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:BMC Biotechnol
Egile Nagusiak: Bouvette, Jonathan, Korkut, Dursun Nizam, Fouillen, Aurélien, Amellah, Soumiya, Nanci, Antonio, Durocher, Yves, Omichinski, James G., Legault, Pascale
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2018
Gaiak:
Methodology Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282390/
https://ncbi.nlm.nih.gov/pubmed/30522464
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12896-018-0485-3
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