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Effects of Dicer and Argonaute down-regulation on mRNA levels in human HEK293 cells
RNA interference and the microRNA (miRNA) pathway can induce sequence-specific mRNA degradation and/or translational repression. The human genome encodes hundreds of miRNAs that can post-transcriptionally repress thousands of genes. Using reporter constructs, we observed that degradation of mRNAs be...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1635286/ https://ncbi.nlm.nih.gov/pubmed/16971455 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkl646 |
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