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EZH2 variants differentially regulate polycomb repressive complex 2 in histone methylation and cell differentiation
BACKGROUND: Polycomb repressive complex 2 (PRC2) is responsible for establishing and maintaining histone H3K27 methylation during cell differentiation and proliferation. H3K27 can be mono-, di-, or trimethylated, resulting in differential gene regulation. However, it remains unknown how PRC2 specifi...
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| Published in: | Epigenetics Chromatin |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6282306/ https://ncbi.nlm.nih.gov/pubmed/30522506 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13072-018-0242-9 |
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