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EZH1 in Germ Cells Safeguards the Function of PRC2 during Spermatogenesis

We previously reported the requirement of Polycomb Repressive Complex 2 (PRC2) for spermatogenesis through transcriptional repression of somatic genes and meiosis-specific genes. To characterize how PRC2’s two methyltransferase subunits, EZH1 and EZH2, regulate histone H3 lysine 27 (H3K27) methylati...

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Detalhes bibliográficos
Publicado no:Dev Biol
Main Authors: Mu, Weipeng, Starmer, Joshua, Shibata, Yoichiro, Yee, Della, Magnuson, Terry
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389884/
https://ncbi.nlm.nih.gov/pubmed/28254491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2017.02.017
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