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Polycomb Repressive Complex 2 is dispensable for maintenance of embryonic stem cell pluripotency

Polycomb Repressive Complex 2 (PRC2) methylates histone H3 tails at lysine 27 and is essential for embryonic development. The three core components of PRC2, Eed, Ezh2, and Suz12, are also highly expressed in embryonic stem (ES) cells where they are postulated to repress developmental regulators and...

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Hlavní autoři: Chamberlain, Stormy J., Yee, Della, Magnuson, Terry
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630378/
https://ncbi.nlm.nih.gov/pubmed/18403752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/stemcells.2008-0102
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