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Polycomb Repressive Complex 2 is dispensable for maintenance of embryonic stem cell pluripotency

Polycomb Repressive Complex 2 (PRC2) methylates histone H3 tails at lysine 27 and is essential for embryonic development. The three core components of PRC2, Eed, Ezh2, and Suz12, are also highly expressed in embryonic stem (ES) cells where they are postulated to repress developmental regulators and...

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Detalhes bibliográficos
Main Authors: Chamberlain, Stormy J., Yee, Della, Magnuson, Terry
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630378/
https://ncbi.nlm.nih.gov/pubmed/18403752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/stemcells.2008-0102
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