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Polycomb Repressive Complex 2 is dispensable for maintenance of embryonic stem cell pluripotency

Polycomb Repressive Complex 2 (PRC2) methylates histone H3 tails at lysine 27 and is essential for embryonic development. The three core components of PRC2, Eed, Ezh2, and Suz12, are also highly expressed in embryonic stem (ES) cells where they are postulated to repress developmental regulators and...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chamberlain, Stormy J., Yee, Della, Magnuson, Terry
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630378/
https://ncbi.nlm.nih.gov/pubmed/18403752
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/stemcells.2008-0102
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