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Polycomb Repressive Complex 2 is dispensable for maintenance of embryonic stem cell pluripotency
Polycomb Repressive Complex 2 (PRC2) methylates histone H3 tails at lysine 27 and is essential for embryonic development. The three core components of PRC2, Eed, Ezh2, and Suz12, are also highly expressed in embryonic stem (ES) cells where they are postulated to repress developmental regulators and...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2630378/ https://ncbi.nlm.nih.gov/pubmed/18403752 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/stemcells.2008-0102 |
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