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Mycobacterium tuberculosis Type VII Secretion System Effectors Differentially Impact the ESCRT Endomembrane Damage Response

Intracellular pathogens have varied strategies to breach the endolysosomal barrier so that they can deliver effectors to the host cytosol, access nutrients, replicate in the cytoplasm, and avoid degradation in the lysosome. In the case of Mycobacterium tuberculosis, the bacterium perforates the phag...

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Detalhes bibliográficos
Publicado no:mBio
Main Authors: Mittal, Ekansh, Skowyra, Michael L., Uwase, Grace, Tinaztepe, Emir, Mehra, Alka, Köster, Stefan, Hanson, Phyllis I., Philips, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282207/
https://ncbi.nlm.nih.gov/pubmed/30482832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01765-18
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