Mycobacterium tuberculosis Type VII Secretion System Effectors Differentially Impact the ESCRT Endomembrane Damage Response

Intracellular pathogens have varied strategies to breach the endolysosomal barrier so that they can deliver effectors to the host cytosol, access nutrients, replicate in the cytoplasm, and avoid degradation in the lysosome. In the case of Mycobacterium tuberculosis, the bacterium perforates the phag...

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Publicado en:mBio
Autores principales: Mittal, Ekansh, Skowyra, Michael L., Uwase, Grace, Tinaztepe, Emir, Mehra, Alka, Köster, Stefan, Hanson, Phyllis I., Philips, Jennifer A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282207/
https://ncbi.nlm.nih.gov/pubmed/30482832
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01765-18
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