Mycobacterium tuberculosis Type VII Secreted Effector EsxH Targets Host ESCRT to Impair Trafficking

Mycobacterium tuberculosis (Mtb) disrupts anti-microbial pathways of macrophages, cells that normally kill bacteria. Over 40 years ago, D'Arcy Hart showed that Mtb avoids delivery to lysosomes, but the molecular mechanisms that allow Mtb to elude lysosomal degradation are poorly understood. Spe...

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Detalhes bibliográficos
Main Authors: Mehra, Alka, Zahra, Aleena, Thompson, Victor, Sirisaengtaksin, Natalie, Wells, Ashley, Porto, Maura, Köster, Stefan, Penberthy, Kristen, Kubota, Yoshihisha, Dricot, Amelie, Rogan, Daniel, Vidal, Marc, Hill, David E., Bean, Andrew J., Philips, Jennifer A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814348/
https://ncbi.nlm.nih.gov/pubmed/24204276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003734
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