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Mycobacterium tuberculosis Type VII Secreted Effector EsxH Targets Host ESCRT to Impair Trafficking

Mycobacterium tuberculosis (Mtb) disrupts anti-microbial pathways of macrophages, cells that normally kill bacteria. Over 40 years ago, D'Arcy Hart showed that Mtb avoids delivery to lysosomes, but the molecular mechanisms that allow Mtb to elude lysosomal degradation are poorly understood. Spe...

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Bibliografiset tiedot
Päätekijät: Mehra, Alka, Zahra, Aleena, Thompson, Victor, Sirisaengtaksin, Natalie, Wells, Ashley, Porto, Maura, Köster, Stefan, Penberthy, Kristen, Kubota, Yoshihisha, Dricot, Amelie, Rogan, Daniel, Vidal, Marc, Hill, David E., Bean, Andrew J., Philips, Jennifer A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Public Library of Science 2013
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3814348/
https://ncbi.nlm.nih.gov/pubmed/24204276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1003734
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