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Mycobacterium tuberculosis EsxH inhibits ESCRT-dependent CD4(+) T-cell activation
Mycobacterium tuberculosis (Mtb) establishes a persistent infection, despite inducing antigen-specific T-cell responses. Although T cells arrive at the site of infection, they do not provide sterilizing immunity. The molecular basis of how Mtb impairs T-cell function is not clear. Mtb has been repor...
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Publicado no: | Nat Microbiol |
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Main Authors: | , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5453184/ https://ncbi.nlm.nih.gov/pubmed/27918526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmicrobiol.2016.232 |
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