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Triggered recruitment of ESCRT machinery promotes endolysosomal repair

Endolysosomes can be damaged by diverse materials. Terminally damaged compartments are degraded by lysophagy, but pathways that repair salvageable organelles are poorly understood. Here we found that the Endosomal Sorting Complex Required for Transport (ESCRT) machinery, known to mediate budding and...

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Pubblicato in:Science
Autori principali: Skowyra, Michael L., Schlesinger, Paul H., Naismith, Teresa V., Hanson, Phyllis I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6195421/
https://ncbi.nlm.nih.gov/pubmed/29622626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aar5078
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