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Growth factor stimulation promotes multivesicular endosome biogenesis by prolonging recruitment of the late-acting ESCRT machinery

The formation of multivesicular endosomes (MVEs) mediates the turnover of numerous integral membrane proteins and has been implicated in the down-regulation of growth factor signaling, thereby exhibiting properties of a tumor suppressor. The endosomal sorting complex required for transport (ESCRT) m...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Quinney, Kyle B., Frankel, Elisa B., Shankar, Raakhee, Kasberg, William, Luong, Peter, Audhya, Anjon
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6452702/
https://ncbi.nlm.nih.gov/pubmed/30894482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1817898116
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