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ESCRT complexes and the biogenesis of multivesicular bodies
Multivesicular bodies (MVBs) are critical intermediates in the trafficking of ubiquitinated receptors and other cargo destined for lysosomes. The formation of MVBs by invagination of the endosomal limiting membrane is catalyzed by the ESCRT complexes, a process that has recently been visualized in t...
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Autor principal: | |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2008
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2282067/ https://ncbi.nlm.nih.gov/pubmed/18222686 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2007.12.002 |
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