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ESCRT complexes and the biogenesis of multivesicular bodies

Multivesicular bodies (MVBs) are critical intermediates in the trafficking of ubiquitinated receptors and other cargo destined for lysosomes. The formation of MVBs by invagination of the endosomal limiting membrane is catalyzed by the ESCRT complexes, a process that has recently been visualized in t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
1. Verfasser: Hurley, James H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2282067/
https://ncbi.nlm.nih.gov/pubmed/18222686
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2007.12.002
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