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Structure and function of the ESCRT II-III interface in multivesicular body biogenesis

The ESCRT-II-ESCRT-III interaction coordinates the sorting of ubiquitinated cargo with the budding and scission of intralumenal vesicles into multivesicular bodies. The interacting regions of these complexes were mapped to the second winged-helix domain of human ESCRT-II subunit VPS25 and the first...

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Autors principals: Im, Young Jun, Wollert, Thomas, Boura, Evzen, Hurley, James H.
Format: Artigo
Idioma:Inglês
Publicat: 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2749878/
https://ncbi.nlm.nih.gov/pubmed/19686684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2009.07.008
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