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Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos

Degradation of most integral membrane proteins is directed by the endosomal sorting complex required for transport (ESCRT) machinery, which selectively targets ubiquitin-modified cargoes into intralumenal vesicles (ILVs) within multivesicular endosomes (MVEs). To better understand the mechanisms und...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Frankel, E. B., Shankar, Raakhee, Moresco, James J., Yates, John R., Volkmann, Niels, Audhya, Anjon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682282/
https://ncbi.nlm.nih.gov/pubmed/29129923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01636-8
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