Ist1 regulates ESCRT-III assembly and function during multivesicular endosome biogenesis in Caenorhabditis elegans embryos

Degradation of most integral membrane proteins is directed by the endosomal sorting complex required for transport (ESCRT) machinery, which selectively targets ubiquitin-modified cargoes into intralumenal vesicles (ILVs) within multivesicular endosomes (MVEs). To better understand the mechanisms und...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Frankel, E. B., Shankar, Raakhee, Moresco, James J., Yates, John R., Volkmann, Niels, Audhya, Anjon
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5682282/
https://ncbi.nlm.nih.gov/pubmed/29129923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01636-8
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