Potent Cas9 Inhibition in Bacterial and Human Cells by AcrIIC4 and AcrIIC5 Anti-CRISPR Proteins

In their natural settings, CRISPR-Cas systems play crucial roles in bacterial and archaeal adaptive immunity to protect against phages and other mobile genetic elements, and they are also widely used as genome engineering technologies. Previously we discovered bacteriophage-encoded Cas9-specific ant...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:mBio
Egile Nagusiak: Lee, Jooyoung, Mir, Aamir, Edraki, Alireza, Garcia, Bianca, Amrani, Nadia, Lou, Hannah E., Gainetdinov, Ildar, Pawluk, April, Ibraheim, Raed, Gao, Xin D., Liu, Pengpeng, Davidson, Alan R., Maxwell, Karen L., Sontheimer, Erik J.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2018
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282205/
https://ncbi.nlm.nih.gov/pubmed/30514786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.02321-18
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