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Para-Toluenesulfonamide Induces Anti-tumor Activity Through Akt-Dependent and -Independent mTOR/p70S6K Pathway: Roles of Lipid Raft and Cholesterol Contents

Castration-resistant prostate cancer (CRPC) cells can resist many cellular stresses to ensure survival. There is an unmet medical need to fight against the multiple adaptive mechanisms in cells to achieve optimal treatment in patients. Para-toluenesulfonamide (PTS) is a small molecule that inhibited...

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書目詳細資料
發表在:Front Pharmacol
Main Authors: Hsu, Jui-Ling, Leu, Wohn-Jenn, Hsu, Lih-Ching, Liu, Shih-Ping, Zhong, Nan-Shan, Guh, Jih-Hwa
格式: Artigo
語言:Inglês
出版: Frontiers Media S.A. 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6282052/
https://ncbi.nlm.nih.gov/pubmed/30555320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01223
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