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Stargazer: a software tool for calling star alleles from next-generation sequencing data using CYP2D6 as a model
PURPOSE: Genotyping CYP2D6 is important for precision drug therapy because it metabolizes approximately 25% of drugs and its activity varies considerably among individuals. Genotype analysis of CYP2D6 is challenging due to its highly polymorphic nature. Over 100 haplotypes (star alleles) have been d...
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| Publicado no: | Genet Med |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6281872/ https://ncbi.nlm.nih.gov/pubmed/29875422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41436-018-0054-0 |
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