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Cell-type-specific miR-431 dysregulation in a motor neuron model of spinal muscular atrophy
Spinal muscular atrophy (SMA) is an autosomal-recessive pediatric neurodegenerative disease characterized by selective loss of spinal motor neurons. It is caused by mutation in the survival of motor neuron 1 , SMN1 , gene and leads to loss of function of the full-length SMN protein. microRNAs (miRNA...
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| Veröffentlicht in: | Hum Mol Genet |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6281359/ https://ncbi.nlm.nih.gov/pubmed/27005422 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw084 |
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