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Cell-type-specific miR-431 dysregulation in a motor neuron model of spinal muscular atrophy

Spinal muscular atrophy (SMA) is an autosomal-recessive pediatric neurodegenerative disease characterized by selective loss of spinal motor neurons. It is caused by mutation in the survival of motor neuron 1 , SMN1 , gene and leads to loss of function of the full-length SMN protein. microRNAs (miRNA...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Wertz, Mary H., Winden, Kellen, Neveu, Pierre, Ng, Shi-Yan, Ercan, Ebru, Sahin, Mustafa
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281359/
https://ncbi.nlm.nih.gov/pubmed/27005422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddw084
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