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Expanded genetic screening in Caenorhabditis elegans identifies new regulators and an inhibitory role for NAD(+) in axon regeneration

The mechanisms underlying axon regeneration in mature neurons are relevant to the understanding of normal nervous system maintenance and for developing therapeutic strategies for injury. Here, we report novel pathways in axon regeneration, identified by extending our previous function-based screen u...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Kim, Kyung Won, Tang, Ngang Heok, Piggott, Christopher A, Andrusiak, Matthew G, Park, Seungmee, Zhu, Ming, Kurup, Naina, Cherra, Salvatore J, Wu, Zilu, Chisholm, Andrew D, Jin, Yishi
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281318/
https://ncbi.nlm.nih.gov/pubmed/30461420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.39756
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