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Expanded genetic screening in Caenorhabditis elegans identifies new regulators and an inhibitory role for NAD(+) in axon regeneration

The mechanisms underlying axon regeneration in mature neurons are relevant to the understanding of normal nervous system maintenance and for developing therapeutic strategies for injury. Here, we report novel pathways in axon regeneration, identified by extending our previous function-based screen u...

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Pubblicato in:eLife
Autori principali: Kim, Kyung Won, Tang, Ngang Heok, Piggott, Christopher A, Andrusiak, Matthew G, Park, Seungmee, Zhu, Ming, Kurup, Naina, Cherra, Salvatore J, Wu, Zilu, Chisholm, Andrew D, Jin, Yishi
Natura: Artigo
Lingua:Inglês
Pubblicazione: eLife Sciences Publications, Ltd 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281318/
https://ncbi.nlm.nih.gov/pubmed/30461420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.39756
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