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Expanded genetic screening in Caenorhabditis elegans identifies new regulators and an inhibitory role for NAD(+) in axon regeneration

The mechanisms underlying axon regeneration in mature neurons are relevant to the understanding of normal nervous system maintenance and for developing therapeutic strategies for injury. Here, we report novel pathways in axon regeneration, identified by extending our previous function-based screen u...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Kim, Kyung Won, Tang, Ngang Heok, Piggott, Christopher A, Andrusiak, Matthew G, Park, Seungmee, Zhu, Ming, Kurup, Naina, Cherra, Salvatore J, Wu, Zilu, Chisholm, Andrew D, Jin, Yishi
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281318/
https://ncbi.nlm.nih.gov/pubmed/30461420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.39756
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