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Calcium and Cyclic AMP Promote Axonal Regeneration in Caenorhabditis elegans and Require DLK-1 Kinase

Axons of adult Caenorhabditis elegans neurons undergo robust regenerative growth after laser axotomy. Here we show that axotomy of PLM sensory neurons triggers axonal calcium waves whose amplitude correlates with the extent of regeneration. Genetic elevation of Ca(2+) or cAMP accelerates formation o...

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書誌詳細
主要な著者: Ghosh-Roy, Anindya, Wu, Zilu, Goncharov, Alexandr, Jin, Yishi, Chisholm, Andrew D.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2921707/
https://ncbi.nlm.nih.gov/pubmed/20203177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5464-09.2010
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