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The DLK-1 kinase promotes mRNA stability and local translation in C. elegans synapses and axon regeneration

Growth cone guidance and synaptic plasticity involve dynamic local changes in proteins at axons and dendrites. The Dual Leucine zipper MAPKKK (DLK) has been previously implicated in synaptogenesis and axon outgrowth in C. elegans and other animals. Here we show that in C. elegans DLK-1 regulates not...

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Detalhes bibliográficos
Principais autores: Yan, Dong, Wu, Zilu, Chisholm, Andrew D., Jin, Yishi
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772821/
https://ncbi.nlm.nih.gov/pubmed/19737525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.06.023
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