Notch1 primes CD4 T cells for T helper type I differentiation through its early effects on miR-29

The transmembrane receptor, Notch1 plays an important role during the differentiation of CD4 T cells into T helper (Th) subsets in the presence of appropriate cytokines, including differentiation into Th1 cells. MicroRNAs have also been shown to be important regulators of immune responses, including...

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Detalhes bibliográficos
Publicado no:Mol Immunol
Main Authors: Chandiran, Karthik, Lawlor, Rebecca, Pannuti, Antonio, Perez, Gabriela Gonzalez, Srinivasan, Janani, Golde, Todd E., Miele, Lucio, Osborne, Barbara A., Minter, Lisa M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281167/
https://ncbi.nlm.nih.gov/pubmed/29807327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2018.05.002
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