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Targeting Cancer Stem Cells through Notch Signaling

The cellular heterogeneity of neoplasms has been at the center of considerable interest since the “cancer stem cell hypothesis”, originally formulated for hematologic malignancies, was extended to solid tumors. The origins of cancer “stem” cells (CSCs) or tumor-initiating cells (TICs) (henceforth re...

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Detalhes bibliográficos
Main Authors: Pannuti, Antonio, Foreman, Kimberly, Rizzo, Paola, Osipo, Clodia, Golde, Todd, Osborne, Barbara, Miele, Lucio
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008160/
https://ncbi.nlm.nih.gov/pubmed/20530696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-2823
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