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Targeting Cancer Stem Cells through Notch Signaling

The cellular heterogeneity of neoplasms has been at the center of considerable interest since the “cancer stem cell hypothesis”, originally formulated for hematologic malignancies, was extended to solid tumors. The origins of cancer “stem” cells (CSCs) or tumor-initiating cells (TICs) (henceforth re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Pannuti, Antonio, Foreman, Kimberly, Rizzo, Paola, Osipo, Clodia, Golde, Todd, Osborne, Barbara, Miele, Lucio
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008160/
https://ncbi.nlm.nih.gov/pubmed/20530696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-09-2823
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