NOTCH-1 and NOTCH-4 are novel gene targets of PEA3 in breast cancer: novel therapeutic implications

INTRODUCTION: Women with triple-negative breast cancer have the worst prognosis, frequently present with metastatic tumors and have few targeted therapy options. Notch-1 and Notch-4 are potent breast oncogenes that are overexpressed in triple-negative and other subtypes of breast cancer. PEA3, an ET...

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Autors principals: Clementz, Anthony G, Rogowski, Allison, Pandya, Kinnari, Miele, Lucio, Osipo, Clodia
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2011
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3218952/
https://ncbi.nlm.nih.gov/pubmed/21679465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr2900
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