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FLT3 inhibitors in acute myeloid leukemia

FLT3 mutations are one of the most common findings in acute myeloid leukemia (AML). FLT3 inhibitors have been in active clinical development. Midostaurin as the first-in-class FLT3 inhibitor has been approved for treatment of patients with FLT3-mutated AML. In this review, we summarized the preclini...

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Pubblicato in:J Hematol Oncol
Autori principali: Wu, Mei, Li, Chuntuan, Zhu, Xiongpeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6280371/
https://ncbi.nlm.nih.gov/pubmed/30514344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-018-0675-4
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