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Mechanisms Underlying Resistance to FLT3 Inhibitors in Acute Myeloid Leukemia
FLT3-ITD and FLT3-TKD mutations were observed in approximately 20 and 10% of acute myeloid leukemia (AML) cases, respectively. FLT3 inhibitors such as midostaurin, gilteritinib and quizartinib show excellent response rates in patients with FLT3-mutated AML, but its duration of response may not be su...
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| Publicado no: | Biomedicines |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7459983/ https://ncbi.nlm.nih.gov/pubmed/32722298 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines8080245 |
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