The anti-cancer activity of a first-in-class small molecule targeting PCNA

PURPOSE: Proliferating cell nuclear antigen (PCNA) plays an essential role in regulating DNA synthesis and repair and is indispensable to cancer cell growth and survival. We previously reported a novel cancer associated PCNA isoform (dubbed caPCNA), which was ubiquitously expressed in a broad range...

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Publicado no:Clin Cancer Res
Main Authors: Gu, Long, Lingeman, Robert, Yakushijin, Fumiko, Sun, Emily, Cui, Qi, Chao, Jianfei, Hu, Weidong, Li, Hongzhi, Hickey, Robert J., Stark, Jeremy M., Yuan, Yate-Ching, Chen, Yuan, Vonderfecht, Steven L., Synold, Timothy W., Shi, Yanhong, Reckamp, Karen L., Horne, David, Malkas, Linda H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279569/
https://ncbi.nlm.nih.gov/pubmed/29967249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-0592
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