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Sequence-function correlation of aromatase and its interaction with reductase

Aromatase is an enzyme required for the conversion of androgens to estrogens. Estrogens are female sex hormones involved in the development and growth of breast tumors. It has been of significant interest to investigate the structure-function relationship of aromatase since its inhibitors have shown...

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Detalhes bibliográficos
Main Authors: Hong, Yanyan, Li, Hongzhi, Yuan, Yate-Ching, Chen, Shiuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836254/
https://ncbi.nlm.nih.gov/pubmed/19944754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsbmb.2009.11.010
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