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Expression of a novel peptide derived from PCNA damages DNA and reverses cisplatin resistance

BACKGROUND: An 8 amino acid peptide sequence derived from proliferating cell nuclear antigen (PCNA) has been shown to effectively kill several breast cancer and neuroblastoma cell lines when added exogenously to cell cultures. METHODS: In this study, the expression of the 8 amino acid peptide sequen...

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Detalhes bibliográficos
Publicado no:Cancer Chemother Pharmacol
Main Authors: Lingeman, Robert G., Hickey, Robert J., Malkas, Linda H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5458613/
https://ncbi.nlm.nih.gov/pubmed/25190177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00280-014-2574-x
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