TLR8 and its endogenous ligand miR-21 contribute to neuropathic pain in murine DRG

Toll-like receptors (TLRs) are nucleic acid–sensing receptors and have been implicated in mediating pain and itch. Here we report that Tlr8(−/−) mice show normal itch behaviors, but have defects in neuropathic pain induced by spinal nerve ligation (SNL) in mice. SNL increased TLR8 expression in smal...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Exp Med
Egile Nagusiak: Zhang, Zhi-Jun, Guo, Jian-Shuang, Li, Si-Si, Wu, Xiao-Bo, Cao, De-Li, Jiang, Bao-Chun, Jing, Peng-Bo, Bai, Xue-Qiang, Li, Chun-Hua, Wu, Zi-Han, Lu, Ying, Gao, Yong-Jing
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Rockefeller University Press 2018
Gaiak:
Research Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279408/
https://ncbi.nlm.nih.gov/pubmed/30455267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20180800
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak