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CXCL10/CXCR3 Signaling in the DRG Exacerbates Neuropathic Pain in Mice
Chemokines and receptors have been implicated in the pathogenesis of chronic pain. Here, we report that spinal nerve ligation (SNL) increased CXCR3 expression in dorsal root ganglion (DRG) neurons, and intra-DRG injection of Cxcr3 shRNA attenuated the SNL-induced mechanical allodynia and heat hypera...
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| Publié dans: | Neurosci Bull |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Springer Singapore
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7955022/ https://ncbi.nlm.nih.gov/pubmed/33196963 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-020-00608-1 |
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