CXCL13 drives spinal astrocyte activation and neuropathic pain via CXCR5

Recent studies have implicated chemokines in microglial activation and pathogenesis of neuropathic pain. C-X-C motif chemokine 13 (CXCL13) is a B lymphocyte chemoattractant that activates CXCR5. Using the spinal nerve ligation (SNL) model of neuropathic pain, we found that CXCL13 was persistently up...

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Veröffentlicht in:J Clin Invest
Hauptverfasser: Jiang, Bao-Chun, Cao, De-Li, Zhang, Xin, Zhang, Zhi-Jun, He, Li-Na, Li, Chun-Hua, Zhang, Wen-Wen, Wu, Xiao-Bo, Berta, Temugin, Ji, Ru-Rong, Gao, Yong-Jing
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4731172/
https://ncbi.nlm.nih.gov/pubmed/26752644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81950
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