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Adaptive Clinical Trials: Advantages and Disadvantages of Various Adaptive Design Elements
There is a wide range of adaptive elements of clinical trial design (some old and some new), with differing advantages and disadvantages. Classical interim monitoring, which adapts the design based on early evidence of superiority or futility of a treatment arm, has long been known to be extremely u...
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| Publicado no: | J Natl Cancer Inst |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6279284/ https://ncbi.nlm.nih.gov/pubmed/28376148 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djx013 |
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