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Design Issues in Randomized Clinical Trials of Maintenance Therapies

A potential therapeutic strategy for patients who respond (or have stable disease) on a fixed-duration induction therapy is to receive maintenance therapy, typically given for a prolonged period of time. To enable patients and clinicians to make informed treatment decisions, the designs of phase III...

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Опубликовано в: :J Natl Cancer Inst
Главные авторы: Freidlin, Boris, Little, Richard F., Korn, Edward L.
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849358/
https://ncbi.nlm.nih.gov/pubmed/26286730
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djv225
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