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Monitoring for Lack of Benefit: A Critical Component of a Randomized Clinical Trial
To balance patient interests against the need for acquiring evidence, ongoing randomized clinical trials are formally monitored for early convincing indication of benefit or lack of benefit. In lethal diseases like cancer, where new therapies are often toxic and may have limited preliminary efficacy...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Clinical Oncology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2645857/ https://ncbi.nlm.nih.gov/pubmed/19064977 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.17.8905 |
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