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Stopping or Reporting Early for Positive Results in Randomized Clinical Trials: The National Cancer Institute Cooperative Group Experience From 1990 to 2005

Randomized clinical trials are designed with stopping boundaries to guide data monitoring committees with their decision making concerning ongoing trials. In particular, when extremely positive results are seen and a boundary is crossed, the data monitoring committee may recommend releasing the resu...

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Détails bibliographiques
Auteurs principaux: Korn, Edward L., Freidlin, Boris, Mooney, Margaret
Format: Artigo
Langue:Inglês
Publié: American Society of Clinical Oncology 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2668973/
https://ncbi.nlm.nih.gov/pubmed/19237631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2008.19.5339
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