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Randomized Clinical Trials With Biomarkers: Design Issues

Clinical biomarker tests that aid in making treatment decisions will play an important role in achieving personalized medicine for cancer patients. Definitive evaluation of the clinical utility of these biomarkers requires conducting large randomized clinical trials (RCTs). Efficient RCT design is t...

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Detalhes bibliográficos
Main Authors: Freidlin, Boris, McShane, Lisa M., Korn, Edward L.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911042/
https://ncbi.nlm.nih.gov/pubmed/20075367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djp477
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