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Randomized Clinical Trials With Biomarkers: Design Issues

Clinical biomarker tests that aid in making treatment decisions will play an important role in achieving personalized medicine for cancer patients. Definitive evaluation of the clinical utility of these biomarkers requires conducting large randomized clinical trials (RCTs). Efficient RCT design is t...

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Hlavní autoři: Freidlin, Boris, McShane, Lisa M., Korn, Edward L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2911042/
https://ncbi.nlm.nih.gov/pubmed/20075367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djp477
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