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Design Issues in Randomized Phase II/III Trials

Phase II trials are used to show sufficient preliminary activity of a new treatment (in single-arm designs or randomized screening designs) or to select among treatments with demonstrated activity (in randomized selection designs). The treatments prioritized in a phase II trial are then tested defin...

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Главные авторы: Korn, Edward L., Freidlin, Boris, Abrams, Jeffrey S., Halabi, Susan
Формат: Artigo
Язык:Inglês
Опубликовано: American Society of Clinical Oncology 2012
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3295562/
https://ncbi.nlm.nih.gov/pubmed/22271475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2011.38.5732
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