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Statistical and Practical Considerations for Clinical Evaluation of Predictive Biomarkers

Predictive biomarkers to guide therapy for cancer patients are a cornerstone of precision medicine. Discussed herein are considerations regarding the design and interpretation of such predictive biomarker studies. These considerations are important for both planning and interpreting prospective stud...

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Detalhes bibliográficos
Main Authors: Polley, Mei-Yin C., Freidlin, Boris, Korn, Edward L., Conley, Barbara A., Abrams, Jeffrey S., McShane, Lisa M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888208/
https://ncbi.nlm.nih.gov/pubmed/24136891
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djt282
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