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Development of omics-based clinical tests for prognosis and therapy selection: The challenge of achieving statistical robustness and clinical utility

BACKGROUND: Many papers have been published in biomedical journals reporting on the development of prognostic and therapy-guiding biomarkers or predictors developed from high-dimensional data generated by omics technologies. Few of these tests have advanced to routine clinical use. PURPOSE: We discu...

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Dettagli Bibliografici
Pubblicato in:Clin Trials
Autori principali: McShane, Lisa M., Polley, Mei-Yin C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4410005/
https://ncbi.nlm.nih.gov/pubmed/24000377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1740774513499458
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