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Two-by-Two Factorial Cancer Treatment Trials: Is Sufficient Attention Being Paid to Possible Interactions?

Factorial 2 × 2 designs can be used to combine evaluation of two treatments in a single study. The standard analysis approach is based on a factorial analysis that evaluates each treatment by pooling data over the other treatment. This approach relies on the assumption that the effect of each treatm...

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Detalles Bibliográficos
Publicado en:J Natl Cancer Inst
Autores principales: Freidlin, Boris, Korn, Edward L.
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6059117/
https://ncbi.nlm.nih.gov/pubmed/28954288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djx146
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