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Antibody-Based In Vivo PET Imaging Detects Amyloid-β Reduction in Alzheimer Transgenic Mice After BACE-1 Inhibition
Visualization of amyloid-β (Aβ) pathology with PET has become an important tool for making a specific clinical diagnosis of Alzheimer disease (AD). However, the available amyloid PET radioligands, such as (11)C-Pittsburgh compound B, reflect levels of insoluble Aβ plaques but do not capture soluble...
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| Publicado no: | J Nucl Med |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Society of Nuclear Medicine
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6278900/ https://ncbi.nlm.nih.gov/pubmed/29853653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.213140 |
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