A Novel Integrated Way for Deciphering the Glycan Code for the FimH Lectin

The fimbrial lectin FimH from uro- and enteropathogenic Escherichia coli binds with nanomolar affinity to oligomannose glycans exposing Manα1,3Man dimannosides at their non-reducing end, but only with micromolar affinities to Manα1,2Man dimannosides. These two dimannoses play a significantly distinc...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Dumych, Tetiana, Bridot, Clarisse, Gouin, Sébastien G., Lensink, Marc F., Paryzhak, Solomiya, Szunerits, Sabine, Blossey, Ralf, Bilyy, Rostyslav, Bouckaert, Julie, Krammer, Eva-Maria
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278545/
https://ncbi.nlm.nih.gov/pubmed/30373288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23112794
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