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Synthesis and testing of the first azobenzene mannobioside as photoswitchable ligand for the bacterial lectin FimH

In order to allow spatial and temporal control of carbohydrate-specific bacterial adhesion, it has become our goal to synthesise azobenzene mannosides as photoswitchable inhibitors of type 1 fimbriae-mediated adhesion of E. coli. An azobenzene mannobioside 2 was prepared and its photochromic propert...

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Bibliografiske detaljer
Main Authors: Chandrasekaran, Vijayanand, Kolbe, Katharina, Beiroth, Femke, Lindhorst, Thisbe K
Format: Artigo
Sprog:Inglês
Udgivet: Beilstein-Institut 2013
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3566865/
https://ncbi.nlm.nih.gov/pubmed/23399876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.9.26
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