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Diazirine-functionalized mannosides for photoaffinity labeling: trouble with FimH
Photoaffinity labeling is frequently employed for the investigation of ligand–receptor interactions in solution. We have employed an interdisciplinary methodology to achieve facile photolabeling of the lectin FimH, which is a bacterial protein, crucial for adhesion, colonization and infection. Follo...
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| Published in: | Beilstein J Org Chem |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Beilstein-Institut
2018
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6071696/ https://ncbi.nlm.nih.gov/pubmed/30112094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.14.163 |
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