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Diazirine-functionalized mannosides for photoaffinity labeling: trouble with FimH

Photoaffinity labeling is frequently employed for the investigation of ligand–receptor interactions in solution. We have employed an interdisciplinary methodology to achieve facile photolabeling of the lectin FimH, which is a bacterial protein, crucial for adhesion, colonization and infection. Follo...

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Bibliografiske detaljer
Udgivet i:Beilstein J Org Chem
Main Authors: Beiroth, Femke, Koudelka, Tomas, Overath, Thorsten, Knight, Stefan D, Tholey, Andreas, Lindhorst, Thisbe K
Format: Artigo
Sprog:Inglês
Udgivet: Beilstein-Institut 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071696/
https://ncbi.nlm.nih.gov/pubmed/30112094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.14.163
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