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Diazirine-functionalized mannosides for photoaffinity labeling: trouble with FimH

Photoaffinity labeling is frequently employed for the investigation of ligand–receptor interactions in solution. We have employed an interdisciplinary methodology to achieve facile photolabeling of the lectin FimH, which is a bacterial protein, crucial for adhesion, colonization and infection. Follo...

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Detalhes bibliográficos
Publicado no:Beilstein J Org Chem
Main Authors: Beiroth, Femke, Koudelka, Tomas, Overath, Thorsten, Knight, Stefan D, Tholey, Andreas, Lindhorst, Thisbe K
Formato: Artigo
Idioma:Inglês
Publicado em: Beilstein-Institut 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071696/
https://ncbi.nlm.nih.gov/pubmed/30112094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.14.163
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