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Diazirine-functionalized mannosides for photoaffinity labeling: trouble with FimH

Photoaffinity labeling is frequently employed for the investigation of ligand–receptor interactions in solution. We have employed an interdisciplinary methodology to achieve facile photolabeling of the lectin FimH, which is a bacterial protein, crucial for adhesion, colonization and infection. Follo...

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Bibliografski detalji
Izdano u:Beilstein J Org Chem
Glavni autori: Beiroth, Femke, Koudelka, Tomas, Overath, Thorsten, Knight, Stefan D, Tholey, Andreas, Lindhorst, Thisbe K
Format: Artigo
Jezik:Inglês
Izdano: Beilstein-Institut 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6071696/
https://ncbi.nlm.nih.gov/pubmed/30112094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3762/bjoc.14.163
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